Thursday, February 20, 2025

The Latest Medical News

A Summary of The Latest Medical News:

## What's New in Medical News?

## **Ketones and Heart Health: A Novel Approach for Type 2 Diabetes** As of recent developments, a small-scale study conducted by the University of Portsmouth has revealed promising results regarding the impact of drinking ketones on heart health for individuals with type 2 diabetes. This innovative approach involves administering ketone esters, which induce a metabolic state known as ketosis, where the body primarily burns fat instead of carbohydrates. The study involved 13 participants who were given a ketone drink, followed by a placebo drink a week later. Notably, all participants showed improved cardiac efficiency at rest and during moderate exercise after consuming the ketone drink compared to the placebo[1][3]. ## **Mechanism and Outcomes** In individuals with type 2 diabetes, the body often relies heavily on fatty acids due to insulin resistance, which can lead to increased heart strain. However, when given ketones before exercise, these individuals demonstrated increased cardiac output, stroke volume, and peripheral muscle oxygenation. These indicators suggest improved heart function, offering a potential therapeutic strategy for enhancing cardiovascular health in this demographic[1][3]. Further research is needed to understand the long-term effects of ketone consumption, as current studies only assess acute responses[3]. ## **Comparison with Other Treatments** The discovery of ketones' positive effects on heart health for diabetes patients builds upon observations of improved cardiovascular outcomes in those treated with sodium-glucose cotransporter-2 inhibitors (SGLT2i). A separate study on a 2-week ketone ester treatment found increased cardiac output and reduced ventricular stiffness in patients with type 2 diabetes and heart failure with preserved ejection fraction (HFpEF)[5]. These findings highlight ketones as a potential modality for improving cardiovascular health in high-risk populations. ## **Future Directions** While these early results are promising, more comprehensive research is necessary to fully understand the chronic impact of ketone supplementation on heart health. As scientists continue to explore the therapeutic potential of ketones, it's crucial to monitor both short-term and long-term effects to determine their viability as a heart health intervention for individuals with type 2 diabetes. Help with your insurance? https://tally.so/r/n012P9

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