Monday, March 3, 2025

The Latest Medical News

A Summary of The Latest Medical News: Artificial Sweetener Linked to Increased Heart Disease Risk A new study published in Cell Metabolism has found a potential link between the artificial sweetener aspartame and an increased risk of cardiovascular disease. Researchers discovered that in mice, aspartame consumption triggered insulin spikes that led to the buildup of fatty plaques in the arteries - a major risk factor for heart attacks and strokes. The study involved feeding mice a diet containing 0.15% aspartame daily for 12 weeks, equivalent to a human drinking about 3 cans of diet soda per day. Compared to control mice, the aspartame-fed mice developed larger fatty plaques in their arteries and showed higher levels of blood vessel inflammation. Analysis revealed that aspartame caused a surge in insulin levels after entering the mice's systems. The artificial sweetener, which is 200 times sweeter than sugar, appeared to trick sweetness-detecting receptors into releasing more insulin than normal. This elevated insulin was found to fuel the growth of arterial plaques. The researchers identified an immune signal called CX3CL1 that becomes especially active under insulin stimulation. This molecule acts like "bait," catching immune cells as they pass through blood vessels and contributing to inflammation. When CX3CL1 receptors were eliminated in the aspartame-fed mice, the harmful plaque buildup did not occur. While these findings are concerning, experts urge caution in interpreting the results. The study was conducted in mice, and human trials are still needed to verify the effects in people. However, it adds to a growing body of research suggesting artificial sweeteners may have negative health impacts when consumed regularly. As artificial sweeteners have become ubiquitous in many foods and drinks, particularly those marketed as diet or sugar-free options, understanding their long-term health effects is crucial. Consumers may want to be mindful of their aspartame intake while awaiting further research. As always, moderation is likely key when it comes to any food additives or substitutes. Help with your insurance? https://tally.so/r/n012P9

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