The Latest Medical News

A Summary of The Latest Medical News: **Alzheimer’s Disease and Sleep: New Hope from an Insomnia Medication** A recent breakthrough in Alzheimer’s research brings unexpected news from the world of sleep medicine. An insomnia drug called **lemborexant** has demonstrated promise in slowing brain changes linked to Alzheimer’s disease, based on a new study involving mice[5][3][1]. **What Is Lemborexant?** Lemborexant is a type of sleep aid known as a **dual orexin receptor antagonist**. Orexin is a protein that helps keep the brain awake and alert, and by blocking it, lemborexant allows for deeper, more restorative sleep[5]. Imagine orexin as a stubborn light switch. If the brain keeps that switch on, it's hard to rest — lemborexant flips that switch off and gives the brain a chance to recharge[5]. **How Does Lemborexant Affect Alzheimer’s Disease?** In this new research, scientists used lemborexant to treat mice that were genetically engineered to develop harmful tau buildup in their brains. In Alzheimer’s, **tau proteins** lose their normal function, twist into tangles, and build up inside brain cells. This disruption leads to cell death, memory loss, confusion, and other hallmarks of Alzheimer’s disease[5]. The study found that mice given lemborexant: - Had **better sleep**, especially more non-REM deep sleep, which helps the brain remove toxins like abnormal tau[1]. - Experienced less brain inflammation and less shrinkage in memory-forming regions, compared to mice that didn’t get the drug or those treated with standard sleeping pills like zolpidem[3][1]. - Showed a **reduction in unhealthy tau buildup**, suggesting that lemborexant might help slow damage at the cellular level[3][1]. **Why Are These Results Exciting?** Current Alzheimer’s treatments focus on another protein called amyloid beta. While these can help in early stages, they do not stop the progression as strongly as hoped[3]. Because this new approach targets the clearing of tau tangles through **improved sleep and orexin inhibition**, it offers a fresh angle for both prevention and treatment — especially since disrupted sleep is common for people living with Alzheimer’s[3][1][5]. **What Does This Mean for the Future?** While these results are from animal studies, they open the door for human trials. For patients and families affected by Alzheimer’s, improving sleep quality could emerge as a key part of care, potentially slowing the disease and enhancing quality of life[1]. Researchers suggest that lemborexant and other “orexin blockers” are worth further study for their neuroprotective potential. Tailored sleep support may eventually become an important strategy in personalized Alzheimer’s disease care, alongside more traditional approaches[1][3][5]. Stay tuned for developments as the intersection between sleep medicine and neurology continues to reveal new hope for Alzheimer’s. Help with your insurance? https://tally.so/r/n012P9

Retirement Concerns on Aging ​

Are you getting to that point in life where age has become a concern? Read on!!! Representatives Attend On Aging 2023 Conference Representatives from the School of Aging Studies recently participated in the On Aging 2023 conference in Atlanta. This event is recognized as the nation's largest multidisciplinary conference focused on aging, bringing together professionals from across the country to discuss the latest trends and challenges in the field[1][4]. Connecting With Aging Professionals During the conference, the representatives shared information about the school’s academic programs. Their engagement offered an opportunity to connect with a broad range of aging professionals and organizations dedicated to advancing health, well-being, and innovation in aging services[1][2][4].

The Latest Medical News

A Summary of The Latest Medical News: **Daily Cup of Beans May Lower Cholesterol and Improve Heart Health** A new medical news highlight reveals that incorporating a **daily cup of beans** into your diet could significantly lower cholesterol levels and benefit heart health. ** Beans are naturally high in fiber and plant-based protein, which are both recognized for their cholesterol-lowering effects. Researchers have observed that individuals who regularly consume beans experience noticeable drops in LDL cholesterol, sometimes called “bad cholesterol.” ** Scientists suggest that even small dietary changes—such as adding one cup of beans per day—may help reduce overall cholesterol and contribute to improved cardiovascular health. This finding points to an accessible way for people to protect their hearts without drastic changes to their lifestyle. ** Health experts recommend choosing a variety of beans, such as black beans, chickpeas, lentils, or kidney beans, for maximum nutritional benefit. These foods can be easily added to salads, soups, or main dishes, making it simple for people to include more beans in their daily meals. ** Medical professionals remind the public that while beans are a heart-healthy food, they should be included as part of a balanced, varied diet and a healthy lifestyle for full cardiovascular benefits. Help with your insurance? https://tally.so/r/n012P9

The Latest Medical News

A Summary of The Latest Medical News: **Can Coffee Help Women Age Healthier?** A recent study is bringing new optimism to coffee drinkers, especially women looking for ways to maintain their health as they age. According to new research from Harvard University, women who drink coffee daily during midlife appear to have a higher chance of remaining free from major chronic illnesses and keeping both their minds and bodies strong as they grow older[1][3][5]. **The 30-Year Study That Brewed These Results** Researchers followed approximately 47,500 women for over three decades, collecting data as far back as the 1980s. The participants, mainly nurses under age 60, answered questions about their diet and beverage choices, including how much coffee, tea, cola, or decaf they drank[1][3]. **What “Healthy Aging” Means in This Study** The study defined “healthy aging” as reaching age 70 without suffering from major chronic diseases, while also preserving physical abilities and mental health. Out of the thousands tracked, nearly 3,700 women met these rigorous standards for healthy aging—and, on average, they drank about three cups of caffeinated coffee per day during midlife[1][3][5]. **The Power of Caffeinated Coffee** For women who regularly drank coffee, each extra cup per day was linked to a 2–5% increase in the chance of healthy aging, up to the equivalent of five small cups daily. Importantly, the health benefits were linked specifically to caffeinated coffee—not tea, decaf, or cola, which showed no similar association. In fact, cola consumption was tied to worse aging outcomes[1][3]. **Should Everyone Start Drinking Coffee?** Lead author Sara Mahdavi cautioned that coffee is not a cure-all, but for those who already enjoy it and tolerate it well, moderate daily consumption appears to be a positive part of a healthy lifestyle. The research adds to the growing body of evidence highlighting the potential benefits of coffee, especially for women as they consider ways to protect their health into old age[1][3]. Help with your insurance? https://tally.so/r/n012P9

The Latest Medical News

A Summary of The Latest Medical News: **New Hope for Resistant Hypertension: Breakthrough Drug Shows Strong Results** A new medication, part of a class called **aldosterone synthase inhibitors**, has shown promising results in a global phase 3 clinical trial for people struggling with uncontrolled or resistant hypertension[1]. **How the New Treatment Works** This drug, **lorundrostat**, works by targeting and inhibiting CYP11B2—an enzyme responsible for aldosterone production in the body. Aldosterone is a hormone that plays a key role in regulating blood pressure but can contribute to dangerous complications, including heart failure and kidney problems, when present at high levels[1]. **Results from the Global Phase 3 Study** The phase 3 Launch-HTN trial, the largest of its kind for this drug class, included a large and diverse group of patients from around the world. The study found that lorundrostat **safely and consistently lowered blood pressure** across all patient groups assessed[1]. **Expert Opinion on the Findings** Dr. Manish Saxena, Clinical Co-Director at the William Harvey Heart Centre and lead investigator on the study, emphasized the significance of these results, noting that more than **40% of adults with hypertension globally are not achieving their target blood pressure** despite available treatments. He highlighted how the aldosterone pathway’s role in blood pressure regulation makes this new drug class a game-changer for patients with difficult-to-control hypertension[1]. **Safety and Implications for Patients** The trial demonstrated a **good safety profile** for lorundrostat, making it a potentially valuable option for patients whose blood pressure hasn’t responded to conventional therapies. This innovation may provide relief for millions who have previously struggled to manage their hypertension effectively[1]. Help with your insurance? https://tally.so/r/n012P9

Retirement Concerns on Aging ​

Are you getting to that point in life where age has become a concern? Read on!!! ## Introduction to the On Aging 2023 Conference The On Aging 2023 conference, hosted by the American Society on Aging (ASA), was held in Atlanta from March 27, 2023. This event is the largest multidisciplinary conference in the country focused on aging, gathering thousands of professionals who support healthy aging to discuss the latest trends and issues affecting older adults and caregivers[2][3]. ## Key Highlights of the Conference - **Theme and Focus**: The conference theme for 2023 was "Advancing Health & Well-being," with programming tracks that included justice and equity, innovation and social impact, health and well-being, economic security, and ageism and culture[4]. - **Presentations and Workshops**: Organizations like PHI participated in several workshops and poster sessions, addressing topics such as workforce development, advocacy strategies, and addressing eldercare workforce shortages[2]. - **Technology and Innovation**: The Age Tech Pavilion stage, sponsored by Older Adults Technology Services (OATS) from AARP, featured panel discussions on technology adoption for older adults, highlighting the collaboration between ASA and OATS[3]. ## Attendees and Participants Representatives from various institutions, including the School of Aging Studies, attended the conference to share information about their academic programs with aging professionals. This event provides a valuable platform for networking, professional development, and collaboration in the field of aging[1][5]. ## Conclusion The On Aging conference serves as a pivotal platform for discussing and addressing the complex issues surrounding aging, fostering innovation, and promoting collaboration among stakeholders in the aging services sector.

The Latest Medical News

A Summary of The Latest Medical News: **New Study Shows Omega-6 Fatty Acids May Lower Heart Disease and Diabetes Risk** A new study indicates that **eating a diet rich in the omega-6 fatty acid linoleic acid may help support cardiometabolic health** and lower an individual's risk of developing type 2 diabetes and heart disease[1][3][5]. **What Are Omega-6 Fatty Acids and Where Are They Found?** Omega-6 fatty acids are a type of **polyunsaturated fat found in many plant-based oils**. Linoleic acid, the primary omega-6, is especially abundant in **vegetable and seed oils** such as soybean and corn oil, as well as in a variety of plant foods[3]. **Challenging the Controversy Around Seed Oils** Seed oils have frequently come under scrutiny, with claims that they could increase inflammation and raise cardiometabolic risk. However, this new research adds to a growing body of evidence suggesting **higher levels of linoleic acid are linked to lower levels of inflammation and improved heart health**[1][3]. **Latest Evidence From Blood Analysis** Researchers analyzed blood samples from nearly 1,900 people. They found that **higher linoleic acid levels in the blood were associated with lower biomarkers of cardiometabolic risk—including markers related to inflammation**, which are linked to chronic conditions like diabetes and heart disease[3]. **Potential for Reducing Chronic Disease and Mortality** A broader review of over 150 publications supports these findings, reporting **lower risks of cardiovascular diseases, cancer, and overall mortality among those with higher omega-6 intake or circulating levels**[5]. The benefits were most notable for coronary heart disease and stroke. **Replacing Saturated Fats With Unsaturated Fats** Experts highlight the importance of **replacing saturated fats (like those found in animal products) with unsaturated fats**—specifically polyunsaturated fatty acids like omega-6s. This dietary shift is shown to be particularly effective in reducing cholesterol and, in turn, improving heart health[1]. **Are There Any Risks?** While most evidence points to health benefits, some research suggests **omega-6 intake may increase the risk for certain cancers, such as ovarian and endometrial cancer**, though it may lower risks for others, like lung and prostate cancer[5]. The protective effects are most pronounced in generally healthy people, and less so for individuals with pre-existing health conditions. **Public Health Impact and Next Steps** These findings suggest **omega-6 fatty acids could play a key role in promoting public health**, especially in preventing diabetes and cardiovascular disease. Nonetheless, researchers emphasize the need for further study to clarify potential risks and understand exactly how these fats impact different health conditions[1][3][5]. Help with your insurance? https://tally.so/r/n012P9

The Latest Medical News

A Summary of The Latest Medical News: **New Study: Keto and Mediterranean Diets Both Help Lower Blood Pressure** A recent study has found that both the **Mediterranean** and **keto diets** can lead to significant reductions in blood pressure, while also supporting weight loss and improving overall cardiovascular health[1]. **Study Details and Diet Comparison** Researchers recruited 26 adults with obesity or who were overweight for this study[1]. Participants were randomly divided: eleven followed the Mediterranean diet while fifteen followed the keto diet over three months[1]. At the end of the three months, both groups **lost weight** and **lowered their blood pressure**, indicating that both approaches can be effective for improving heart health[1]. **Additional Benefits Noted** In addition to these primary findings, both diet groups experienced an **increase in fat-free mass** (which means an increase in lean body tissue), and a reduction in body fat, blood lipid levels, and insulin concentrations[1]. This suggests that whether you choose keto or Mediterranean, you might see improvements not only in weight and blood pressure but also in general metabolic health. **Nocturnal Dipping: Subtle But Important Difference** One difference did emerge between the diets. The researchers observed that participants on the keto diet exhibited a greater “**nocturnal dipping**”—the normal drop in blood pressure that happens during sleep—compared to those on the Mediterranean diet[1]. Healthy nocturnal dipping is a good sign for blood pressure regulation and long-term heart health[1]. Abnormal patterns have been linked to higher risks of heart disease. **Expert Perspective** Cheng-Han Chen, MD, an interventional cardiologist, explained the significance of nocturnal dipping, noting it’s a marker for healthy blood pressure rhythms and can influence cardiovascular risk[1]. **Takeaway: Both Diets Work—With Nuances** In summary, **both the Mediterranean and keto diets can help people lose weight, lower blood pressure, and enhance metabolic health**. Choosing between them may come down to personal preferences, specific health considerations, and sustainability. Notably, the study suggests there may be nuanced benefits to each, such as improved nocturnal blood pressure regulation on keto[1]. Help with your insurance? https://tally.so/r/n012P9

The Latest Medical News

A Summary of The Latest Medical News: **Sugary Drinks Linked to Increased Diabetes Risk** A new meta-study has found that **regular consumption of sugar-sweetened drinks—such as sodas, sports drinks, and energy drinks—may significantly raise the risk of developing type 2 diabetes**[1][3][5]. For each 12-ounce serving of these drinks consumed daily, the risk increases by approximately 25% relative to individuals who do not regularly drink them[1]. **Fruit Juice Also Raises the Risk, But Less Than Soda** Although **fruit juice is often perceived as a healthier alternative**, the study found that each serving of fruit juice increased diabetes risk by about 5%[1]. While better than sodas in some aspects, fruit juices still contain a substantial amount of sugar and contribute to elevated risk when consumed frequently[3]. **Sugar in Food: Not the Same as Sugar in Drinks** Surprisingly, the researchers noted that **eating moderate amounts of sugar with or in foods did not show the same risk**. In fact, an intake of about 20 grams of sugar per day from foods was associated with a lower risk of developing type 2 diabetes, contrasting sharply with the findings for sugary drinks[1][3]. **Why ‘Drinking Your Sugar’ Is More Problematic** The lead author, Dr. Karen Della Corte, emphasized that their research demonstrates the source of sugar makes a difference. “It highlights why drinking your sugar—whether from soda or juice—is more problematic for health than eating it,” she said. The body responds differently to liquid sugars, which can quickly spike blood sugar levels and contribute to weight gain, a known risk factor for type 2 diabetes[3][5]. **Replacing Sugary Drinks Makes a Difference** The evidence suggests that **replacing one daily serving of a sugary beverage with water, coffee, or tea may lower diabetes risk by 2–10%**[5]. Simply reducing your intake of sugary drinks or substituting them with healthier options could have significant benefits for diabetes prevention. **Key Takeaway** If you’re concerned about diabetes, **cutting back on sugar-sweetened drinks should be a top priority**. Eating moderate amounts of sugar with your food appears much less risky, while fruit juices and sodas—even in modest amounts—can raise your risk of type 2 diabetes. Help with your insurance? https://tally.so/r/n012P9