Wednesday, November 12, 2025

The Latest Medical News

A Summary of The Latest Medical News: Vitamin D Supplements: D3 May Be More Beneficial Than D2 A new meta-analysis reveals that **vitamin D2 supplements may negatively impact circulating levels of vitamin D3**, which can negate the benefits of the latter form of the vitamin[1][5][6]. **Key Differences Between Vitamin D2 and D3** Vitamin D supplements come in two forms: **vitamin D2 (ergocalciferol) and vitamin D3 (cholecalciferol)**. Both are used to treat vitamin D deficiency, a condition linked to risks like rickets, osteomalacia, cardiovascular issues, and autoimmune diseases[1][4][7]. **Meta-Analysis Findings** Researchers systematically reviewed previous randomized controlled trials to **investigate the impact of vitamin D2 supplementation on vitamin D3 levels**. They found that those receiving vitamin D2 supplements experienced a significant decline in circulating vitamin D3 compared to individuals who received a placebo or no supplementation[1][2][5]. **Impact on Health** Vitamin D3 is essential for **bone and immune health**. The reduction of its levels caused by vitamin D2 supplementation could diminish these benefits and impact key functions in the body[3][6]. **Expert Recommendations** Given the findings, medical experts now **recommend prioritizing vitamin D3 supplements** for most people. Doctors should consider D2 supplementation only for individuals avoiding animal-derived products and should monitor vitamin D3 levels specifically when treating deficiency[1][3]. **Implications for Supplement Choices** The discovery that vitamin D2 can lower vitamin D3 marks a shift in how clinicians and consumers should think about vitamin D supplementation, emphasizing the superior effectiveness and health benefits of D3[1][3][6]. **Inclusivity Considerations** The study also highlights the need for **greater access to vegan-friendly vitamin D3 sources** to ensure those who avoid animal products can still maintain optimal vitamin D levels[3]. **Summary** Emerging evidence strongly suggests that **vitamin D3 supplements are more beneficial than vitamin D2**, especially for maintaining healthy vitamin D status and supporting bone and immune health. Prioritizing D3 supplementation is now considered best practice for most individuals[1][3][6]. Help with your insurance? https://tally.so/r/n012P9

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